High Blood Sugar a High Risk Even Without a Diabetes Diagnosis
A retrospective study of 605 COVID-19 patients in Wuhan, China found hyperglycemia increases the risk of severe complications while more than doubling the risk of death.
The study worked to assess 605 COVID-19 patients for outcomes and complications after 28-days comparing them to fasting blood glucose measurements at admission from January, 24 2020 to February 10, 2020 in two hospitals in Wuhan, China.
The study found that those in the highest fasting blood glucose group were 2.3 times more likely to die than those in the lowest. While the pre-diabetic group was 71% more likely to die than those in the lowest group.
It was noted by the study authors that increasing mortality in the hyperglycemia groups were likely due to a high blood glucose's contribution to increased clotting, worsened blood vessel function, and an exaggerated cytokine storm.
The study authors made the following conclusions and suggestions:
"A fasting blood glucose level of 7.0 mmol/l or higher at admission is an independent predictor for 28-day mortality in patients with COVID-19 without previous diagnosis of diabetes. Blood sugar testing and control should be recommended to all COVID-19 patients even if they do not have pre-existing diabetes, as most COVID-19 patients are prone to glucose metabolic disorders. During a pandemic of COVID-19, measuring fasting blood glucose can facilitate the assessment of prognosis and early intervention of hyperglycaemia to help improve the overall outcomes in treatment of COVID-19."