New Study's Data Conflicts with what We
Know about Asymptomatic Covid-19 Patients
June 18th -
Recent research data conflicts with what we know about asymptomatic patients.
In the study, 37 asymptomatic cases were tracked, defined as individuals with a positive nucleic acid test result but without any relevant clinical symptoms in the preceding 14 d and during hospitalization.
These were compared to a total of 178 peer patients who were confirmed to have SARS-CoV-2 infections in the Wanzhou District of China, as pulled from the same quarantine testing pool.
The key results were:
Of the 178 laboratory-confirmed patients, 37 who never developed any symptoms throughout the disease course were included in this study, this equates to 20.8% of patients having asymptomatic infections.
The proportion of asymptomatic infections might be even higher as some cases might be missed by RT–PCR testing. The study successfully identified seven patients who had active SARS-CoV-2 infection from 148 cases that had negative RT–PCR results and no symptoms by using an antibody test
A possible reversal of previously documented data, among asymptomatic patients it was found the median duration of viral shedding was 19 days, compared to 14 days for those who had mild symptoms.
Asymptomatic individuals exhibited lower levels of 18 different pro and anti-inflammatory cytokines. These data suggest that asymptomatic individuals had a weaker immune response to SARS-CoV-2 infection.